Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119157 | 0.86 | MEN1 (0.52) | CNR2CNR1MAPTMEN1ALDH1A1 | |
| SCHEMBL9120343 | 0.86 | MAPT (0.44) | MAPTMEN1KMT2ACYP4A11CYP4F2 | |
| SCHEMBL9122500 | 0.82 | PPARD (0.53) | ALDH1A1PPARG | |
| SCHEMBL9121261 | 0.79 | PDE3B (0.46) | CNR2CNR1MAPTMEN1ALDH1A1 | |
| SCHEMBL9121570 | 0.77 | LTB4R (0.47) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL9673644 | 0.76 | CYP4A11 (0.63) | CYP4A11CYP4F2 | |
| SCHEMBL1270074 | 0.76 | HDAC1 (0.55) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31155856 | 0.76 | MAPT (0.60) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL27088423 | 0.76 | MEN1 (0.67) | CNR2CNR1MEN1ALDH1A1KMT2A | |
| SCHEMBL27403097 | 0.76 | PTPN1 (0.56) | MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273999-A | A 4-keto-boroalkyleneoxychroman or 2,3-dihydrobenzofuran derivative | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |