Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | CTRC | Q99895 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619973 | 0.77 | FAAH (0.34) | — | |
| SCHEMBL21601874 | 0.77 | PRSS1 (0.39) | PRSS1CTRCF2 | |
| SCHEMBL26466558 | 0.77 | PRSS1 (0.39) | PRSS1CTRCF2 | |
| SCHEMBL10939581 | 0.77 | PRSS1 (0.39) | PRSS1CTRCF2 | |
| SCHEMBL18022061 | 0.76 | PRSS1 (0.34) | PRSS1CTRCF2 | |
| SCHEMBL14503064 | 0.74 | PRSS1 (0.40) | PRSS1CTRCF2 | |
| SCHEMBL11431438 | 0.72 | ALDH1A1 (0.41) | PRSS1CTRCF2 | |
| SCHEMBL10689074 | 0.70 | PRSS1 (0.33) | PRSS1CTRCF2 | |
| SCHEMBL18250958 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL11431872 | 0.67 | PRSS1 (0.32) | PRSS1CTRCF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216175-A | Polyoxoheterocyclic tetracylic derivatives | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0479970-A1 | ANTIMALARIAL ANALOGS OF ARTEMISININ | SRI INTERNATIONAL (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991014689-A1 | ANTIMALARIAL ANALOGS OF ARTEMISININ | SRI INTERNATIONAL (US) | 1991-10-03 | — | — | WO | disclosed |