Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 10/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 10/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.52 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519229 | 0.94 | S1PR2 (0.50) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL7575850 | 0.92 | S1PR2 (0.53) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9445908 | 0.89 | FOLH1 (0.42) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4260452 | 0.78 | LMNA (0.42) | LMNANFKB1PMP22 | |
| SCHEMBL18045572 | 0.78 | MAOA (0.46) | LMNANFKB1PMP22 | |
| Medronic Acid SCHEMBL7764860 | 0.77 | KDM4E (0.48) | LMNABLMFOLH1 | |
| SCHEMBL25356130 | 0.77 | KDM4A (0.43) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL18045569 | 0.76 | MAOA (0.50) | LMNANFKB1PMP22 | |
| SCHEMBL18045567 | 0.76 | MAOA (0.50) | LMNANFKB1PMP22 | |
| SCHEMBL288365 | 0.74 | LMNA (0.53) | LMNANFKB1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |
| US-4131448-A | HERBICIDE | MONSANTO COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4130412-A | HERBICIDE | MONSANTO COMPANY (US) | 1978-12-19 | — | — | US | disclosed |
| US-4062669-A | N-Organo-N-phosphonomethylglycine-N-oxides and plant growth regulant and phytotoxicant compositions containing same | MONSANTO COMPANY (US) | 1977-12-13 | — | — | US | disclosed |