Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13136704 | 0.88 | PKM (0.42) | LMNAMAPTKMT2AMEN1KDM4E | |
| SCHEMBL9279388 | 0.87 | KMT2A (0.40) | LMNAMAPTKMT2AMEN1WDR5 | |
| SCHEMBL9446025 | 0.87 | KMT2A (0.40) | L3MBTL1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL9708898 | 0.86 | WDR5 (0.42) | MAPTKMT2AWDR5TSHRHSP90AA1 | |
| SCHEMBL9445958 | 0.83 | KMT2A (0.38) | MAPTKMT2AMEN1KDM4EWDR5 | |
| SCHEMBL9446038 | 0.83 | WDR5 (0.38) | LMNAMAPTKMT2AKDM4EWDR5 | |
| SCHEMBL9446042 | 0.83 | KMT2A (0.38) | MAPTKMT2AMEN1POLBKDM4E | |
| SCHEMBL4958916 | 0.83 | KMT2A (0.41) | MAPTKMT2AMEN1KDM4EWDR5 | |
| SCHEMBL9812452 | 0.83 | KMT2A (0.41) | MAPTKMT2AMEN1KDM4EWDR5 | |
| SCHEMBL5197626 | 0.83 | KMT2A (0.41) | MAPTKMT2AMEN1KDM4EWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215974-A | Antisecretory agents for gastrointestinal disorders; water solubility, chemical stability | AKTIEBOLAGET HASSLE (SE) | 1993-06-01 | — | — | US | disclosed |
| EP-0279149-B1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Aktiebolaget Hässle (SE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0332647-A1 | NEW BENZIMIDAZOLE DERIVATIVES A PROCESS FOR PRODUCTION THEREOF AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Aktiebolaget Hässle (SE) | 1989-09-20 | — | — | EP | disclosed |
| EP-0279149-A2 | Benzimidazole derivatives, process for their production and a pharmaceutical composition containing the same | Aktiebolaget Hässle (SE) | 1988-08-24 | — | — | EP | disclosed |
| WO-1988003921-A1 | NEW BENZIMIDAZOLE DERIVATIVES A PROCESS FOR PRODUCTION THEREOF AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Aktiebolaget Hässle (SE) | 1988-06-02 | — | — | WO | disclosed |