Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 8/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489119 | 0.84 | KIF11 (0.39) | KMT2AMEN1ELANEKIF11MAPT | |
| SCHEMBL9872014 | 0.79 | KIF11 (0.43) | ELANEKIF11MAPTTDP1L3MBTL1 | |
| SCHEMBL11444278 | 0.78 | KMT2A (0.58) | KMT2AMEN1ELANEMAPTHTT | |
| SCHEMBL10339424 | 0.77 | KMT2A (0.45) | KMT2AMEN1ELANEMAPTTDP1 | |
| SCHEMBL47809 | 0.77 | MAPT (0.61) | KMT2AMEN1ELANEMAPTTDP1 | |
| SCHEMBL1720744 | 0.77 | KIF11 (0.63) | KMT2AMEN1KIF11 | |
| SCHEMBL1788787 | 0.74 | ELANE (0.47) | KMT2AMEN1ELANEKIF11MAPT | |
| SCHEMBL236826 | 0.74 | MAPT (0.53) | KMT2AMEN1ELANEMAPTTDP1 | |
| SCHEMBL56865 | 0.73 | KMT2A (0.50) | KMT2AMEN1ELANEMAPTTSHR | |
| SCHEMBL477017 | 0.72 | MAPT (0.56) | KMT2AMEN1ELANEMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59170033-A | — | — | None | — | — | JP | disclosed |
| JP-59001438-A | — | — | None | — | — | JP | disclosed |
| JP-59001444-A | — | — | None | — | — | JP | disclosed |
| EP-0506760-A4 | CATALYTIC METHOD TO PRODUCE HYDROXY SUBSTITUTED ARYLOPHENONES | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0506760-A1 | CATALYTIC METHOD TO PRODUCE HYDROXY SUBSTITUTED ARYLOPHENONES | THE DOW CHEMICAL COMPANY (US) | 1992-10-07 | — | — | EP | disclosed |
| WO-1991009003-A1 | CATALYTIC METHOD TO PRODUCE HYDROXY SUBSTITUTED ARYLOPHENONES | THE DOW CHEMICAL COMPANY (US) | 1991-06-27 | — | — | WO | disclosed |
| US-5015778-A | Catalytic method to produce hydroxy substituted arylophenones | THE DOW CHEMICAL COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0140050-B1 | HEAT SENSITIVE RECORD MATERIAL | HODOGAYA CHEMICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |
| US-4550329-A | CONTAINING HYDROXY SUBSTITUTED BENZOPHENONE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| EP-0140050-A1 | Heat sensitive record material | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-05-08 | — | — | EP | disclosed |
| JP-S59170033-A | PRODUCTION OF HYDROXYBENZOPHENONE COMPOUND | HODOGAYA CHEM CO LTD | 1984-09-26 | — | — | JP | disclosed |
| JP-S591444-A | PREPARATION OF BIS(2-CHLORO-4-TRIFLUOROMETHYLPHENYL) CARBONATE | HODOGAYA CHEM CO LTD | 1984-01-06 | — | — | JP | disclosed |
| JP-S591438-A | PREPARATION OF 4,4'-DIHYDROXYBENZOPHENONE | HODOGAYA CHEM CO LTD | 1984-01-06 | — | — | JP | disclosed |