SCHEMBL1720744

SCHEMBL1720744

O=C(Oc1ccc(C(F)(F)F)cc1)Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.63
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
ALDH1A1 P00352 1/20 0.49
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
EPHX2 P34913 1/20 0.47
CYP11B1 P15538 1/20 0.46
CYP11B2 P19099 1/20 0.46
TRPV1 Q8NER1 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
SRD5A2 P31213 1/20 0.45
MAOB P27338 2/20 0.45
CYP1A2 P05177 1/20 0.44
PTPN1 P18031 1/20 0.44
GSK3B P49841 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10708455 0.92 KIF11 (0.56) KIF11CES2CES1PRSS1ACR
SCHEMBL10706859 0.90 KIF11 (0.54) KIF11CES2CES1PRSS1ACR
SCHEMBL10706875 0.90 KIF11 (0.54) KIF11CES2CES1PRSS1ACR
SCHEMBL697018 0.88 KIF11 (0.56) KIF11CES2CES1PRSS1ACR
SCHEMBL697017 0.88 KIF11 (0.56) KIF11CES2CES1PRSS1ACR
SCHEMBL10706993 0.87 KIF11 (0.51) KIF11CES2CES1PRSS1ACR
SCHEMBL10710562 0.86 KIF11 (0.58) KIF11PRSS1ACRALDH1A1EPHX2
SCHEMBL12704880 0.84 KIF11 (0.61) KIF11CES2CES1PRSS1ACR
SCHEMBL15453601 0.84 KIF11 (0.61) KIF11CES2CES1PRSS1ACR
SCHEMBL21991236 0.83 KIF11 (0.51) KIF11CES2CES1PRSS1ACR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2406257-B1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA P LTD (IN) 2019-08-07 EP claimed
US-8283470-B2 Method for the preparation of solifenacin and intermediate thereof MEGAFINE PHARMA(P) LTD. (IN) 2012-10-09 US claimed
EP-2406257-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF Megafine Pharma (P) Ltd. (IN) 2012-01-18 EP claimed
US-20110319621-A1 METHOD FOR THE PREPARATION OF SOLIFENACIN AND INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2011-12-29 US claimed
WO-2010103529-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2010-09-16 WO claimed
EP-1504048-B1 METHOD OF PREPARING POLYESTERCARBONATES GEN ELECTRIC (US) 2007-11-21 EP claimed
EP-1504048-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-02-09 EP claimed
WO-2003087190-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-10-23 WO claimed
US-6600004-B1 Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic GENERAL ELECTRIC COMPANY 2003-07-29 US claimed
JP-59001444-A None JP disclosed
JP-59013749-A None JP disclosed
WO-2025121420-A1 POLYCARBONATE AND METHOD FOR PRODUCING THE SAME AGC株式会社 2025-06-12 WO disclosed
US-20240117113-A1 METHOD FOR PRODUCING POLYCARBONATE AGC Inc. (JP) 2024-04-11 US disclosed
EP-4342928-A1 METHOD FOR PRODUCING POLYCARBONATE AGC INC. (JP) 2024-03-27 EP disclosed
US-6600004-B1 Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic GENERAL ELECTRIC COMPANY 2003-07-29 US disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed
EP-0184012-B1 LIQUID CRYSTAL COMPOSITIONS BAYER AG (DE) 1988-01-07 EP disclosed
EP-0184012-A1 Liquid crystal compositions BAYER AG (DE) 1986-06-11 EP disclosed
JP-S5913749-A PREPARATION OF 4-TRIFLUOROMETHYL-4'-NITRODIPHENYL ETHER COMPOUND HODOGAYA CHEM CO LTD 1984-01-24 JP disclosed
JP-S591444-A PREPARATION OF BIS(2-CHLORO-4-TRIFLUOROMETHYLPHENYL) CARBONATE HODOGAYA CHEM CO LTD 1984-01-06 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319621-A1 METHOD FOR THE PREPARATION OF SOLIFENACIN AND INTERMEDIATE THEREOF CHRM3, CHRNA1, ADRA1A KIF11 4272/4885CES2 3122/4885CES1 2718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.