Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445917 | 0.82 | HDAC1 (0.41) | MEN1KMT2AALDH1A1KDM4EHDAC1 | |
| SCHEMBL14809781 | 0.76 | MEN1 (0.43) | POLBMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4411677 | 0.76 | NPSR1 (0.47) | POLBMEN1KMT2ANPSR1LTA4H | |
| SCHEMBL12229683 | 0.76 | POLB (0.53) | POLBMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL14809313 | 0.75 | MEN1 (0.48) | POLBMEN1KMT2ANPSR1LTA4H | |
| SCHEMBL1279290 | 0.75 | SLC2A4 (0.51) | MEN1KMT2AKDM4EMEP1BMAPT | |
| SCHEMBL9446003 | 0.74 | KDM4E (0.54) | MEN1KMT2AKDM4EHDAC1MEP1B | |
| SCHEMBL16702357 | 0.74 | MEN1 (0.48) | POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL13194411 | 0.74 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4EHDAC1 | |
| SCHEMBL3912954 | 0.74 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |