Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445980 | 0.87 | HPGD (0.39) | HDAC1CCNT1CDK9MEN1KMT2A | |
| SCHEMBL9446009 | 0.82 | POLB (0.41) | HDAC1CCNT1CDK9MEN1KMT2A | |
| SCHEMBL3390402 | 0.80 | CCNT1 (0.46) | HDAC1CCNT1CDK9EGFR | |
| SCHEMBL9446021 | 0.79 | LTA4H (0.45) | HDAC1KMT2AALDH1A1PPID | |
| SCHEMBL9445924 | 0.79 | TSHR (0.46) | CCNT1CDK9MEN1KMT2AKDM4E | |
| SCHEMBL9445914 | 0.78 | MEN1 (0.48) | HDAC1CCNT1CDK9MEN1KMT2A | |
| SCHEMBL9445912 | 0.78 | MEN1 (0.48) | HDAC1CCNT1CDK9MEN1KMT2A | |
| SCHEMBL498351 | 0.76 | LOXL2 (0.57) | HDAC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9445923 | 0.76 | MEN1 (0.46) | HDAC1CCNT1CDK9MEN1KMT2A | |
| SCHEMBL9445926 | 0.76 | MEN1 (0.46) | HDAC1CCNT1CDK9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |