Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23703051 | 0.87 | CYP1A2 (0.50) | KDM4ECYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL14432356 | 0.85 | TAAR1 (0.55) | KDM4ECYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL31393609 | 0.85 | CYP1A2 (0.55) | KDM4ECYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL4269762 | 0.84 | CYP1A2 (0.62) | CYP1A2CYP2D6CYP2C19CYP3A4GLA | |
| SCHEMBL1279290 | 0.83 | SLC2A4 (0.51) | KDM4ECYP1A2LMNACYP3A4MEP1B | |
| SCHEMBL11953351 | 0.81 | HDAC1 (0.54) | CYP1A2CYP2D6CYP2C19LMNACYP3A4 | |
| SCHEMBL3912954 | 0.81 | MEN1 (0.44) | KDM4EHPGDMEP1BMEN1KMT2A | |
| SCHEMBL13194411 | 0.81 | MEN1 (0.44) | KDM4EMEP1BMEN1KMT2AHDAC1 | |
| SCHEMBL16702357 | 0.81 | MEN1 (0.48) | MEN1KMT2AFFAR1 | |
| SCHEMBL136054 | 0.80 | SLC7A5 (0.55) | CYP1A2CYP2D6CYP2C19LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132149-A1 | Bridged Cyclic 5-Amino-6,8-Dihydro-1H-Furo[3,4-D]Pyrrolo[3,2-B]Pyridine-2-Carboxamide Compounds, Compositions Thereof, and Methods of Treatment Therewith | BEONE MEDICINES I GMBH (CH) | 2026-05-14 | — | — | US | disclosed |
| US-8557552-B2 | Selective neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2013-10-15 | — | — | US | disclosed |
| US-8557552-B2 | Selective neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2013-10-15 | — | — | US | disclosed |
| US-20120258513-A1 | Selective Neuronal Nitric Oxide Synthase Inhibitors | NORTHWESTERN UNIVERSITY | 2012-10-11 | — | — | US | disclosed |
| US-20120258513-A1 | Selective Neuronal Nitric Oxide Synthase Inhibitors | NORTHWESTERN UNIVERSITY | 2012-10-11 | — | — | US | disclosed |
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120258513-A1 | Selective Neuronal Nitric Oxide Synthase Inhibitors | NOS2, NOS1, NOS3 | KDM4E 2122/4885CYP1A2 540/4885CYP2D6 1598/4885 |
| US-20260132149-A1 | Bridged Cyclic 5-Amino-6,8-Dihydro-1H-Furo[3,4-D]Pyrrolo[3,2-B]Pyridine-2-Carboxamide Compounds, Compositions Thereof, and Methods of Treatment Therewith | MECP2, PRMT5, DNMT1 | KDM4E 79/4885CYP1A2 4474/4885CYP2D6 2895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.