SCHEMBL9446372

SCHEMBL9446372

C=COC(CCC)OC(=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
SOAT1 P35610 1/20 0.38
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.31
CTSK P43235 2/20 0.30
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9300007 0.89 TSHR (0.35) TSHRHPGDCTSK
SCHEMBL429578 0.86 CA1 (0.35) TSHRCTSKCA1CA2
SCHEMBL3884180 0.80 TSHR (0.34) TSHRCTSK
SCHEMBL75914 0.79 TSHR (0.31) TSHR
SCHEMBL8962107 0.79 TSHR (0.44) ALDH1A1TSHRHPGDCTSKHSD17B10
SCHEMBL1470222 0.78 ALDH1A1 (0.46) ALDH1A1SOAT1TSHRLMNAHSD17B10
SCHEMBL1471590 0.78 ALDH1A1 (0.46) ALDH1A1SOAT1TSHRLMNAHSD17B10
SCHEMBL27705392 0.76 ALDH1A1 (0.38) ALDH1A1TSHRCTSK
SCHEMBL5156845 0.75 ALDH1A1 (0.57) ALDH1A1SOAT1LMNAHSD17B10
SCHEMBL285037 0.74 CHRM1 (0.32) TSHRHPGDCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514482-A4 VINYL ETHER COMPOUNDS 1993-04-21 EP disclosed
EP-0514482-A1 VINYL ETHER COMPOUNDS ISP INVESTMENTS INC. (US) 1992-11-25 EP disclosed
WO-1991013052-A1 VINYL ETHER COMPOUNDS ISP INVESTMENTS INC. (US) 1991-09-05 WO disclosed