Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429578 | 0.92 | CA1 (0.35) | TSHRCTSKCHRM1AKR1A1CHRM3 | |
| SCHEMBL9446372 | 0.89 | ALDH1A1 (0.40) | TSHRCTSKHPGD | |
| SCHEMBL3884180 | 0.86 | TSHR (0.34) | TSHRCTSKCHRM1AKR1A1CHRM3 | |
| SCHEMBL75914 | 0.85 | TSHR (0.31) | TSHR | |
| SCHEMBL8962107 | 0.85 | TSHR (0.44) | TSHRCTSKCHRM1AKR1A1CHRM3 | |
| SCHEMBL27705392 | 0.82 | ALDH1A1 (0.38) | TSHRCTSK | |
| SCHEMBL285037 | 0.80 | CHRM1 (0.32) | TSHRCTSKCHRM1AKR1A1CHRM3 | |
| SCHEMBL4640184 | 0.79 | TAS1R3 (0.40) | TSHRCHRM1SLC6A3TDP1CYP3A4 | |
| SCHEMBL2193181 | 0.79 | ALDH1A1 (0.37) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL12965759 | 0.79 | PRKCA (0.50) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364691-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5358978-A | Protective coatings and reactant diluents; wear resistance; solvent, acid and alkali resistance; photoresists | ISP INVESTMENTS INC. (US) | 1994-10-25 | — | — | US | disclosed |
| US-5276174-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-01-04 | — | — | US | disclosed |
| US-5254710-A | Radiation curable | ISP INVESTMENTS INC. (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0514482-A4 | VINYL ETHER COMPOUNDS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0514482-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| US-5159098-A | Alk-1-enyloxy carbamates | ISP INVESTMENTS INC. (US) | 1992-10-27 | — | — | US | disclosed |
| WO-1991013052-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1991-09-05 | — | — | WO | disclosed |