Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300010 | 0.90 | TSHR (0.48) | ALDH1A1TSHRHPGDCYP3A4ATM | |
| SCHEMBL10344245 | 0.83 | ALDH1A1 (0.72) | ALDH1A1SOAT1TSHRATMNAAA | |
| SCHEMBL429579 | 0.82 | TSHR (0.42) | ALDH1A1TSHRHPGDCYP3A4ATM | |
| SCHEMBL8736966 | 0.81 | ATM (0.55) | ALDH1A1TSHRHPGDCYP3A4ATM | |
| SCHEMBL8736969 | 0.81 | ATM (0.55) | ALDH1A1TSHRHPGDCYP3A4ATM | |
| SCHEMBL6940068 | 0.81 | ALDH1A1 (0.68) | ALDH1A1SOAT1TSHRCYP3A4NAAA | |
| SCHEMBL25363687 | 0.81 | TSHR (0.67) | ALDH1A1SOAT1TSHRHPGDCYP3A4 | |
| SCHEMBL9181867 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SOAT1TSHRHPGDCYP3A4 | |
| SCHEMBL1470057 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SOAT1TSHRHPGDATM | |
| SCHEMBL18768627 | 0.79 | TSHR (0.39) | ALDH1A1TSHRHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514482-A4 | VINYL ETHER COMPOUNDS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0514482-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991013052-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1991-09-05 | — | — | WO | disclosed |