Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 6/20 | 0.40 |
| ▸ | NOS1 | P29475 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142527 | 0.79 | MAPT (0.48) | MAPTNPC1MAPK1RAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL9015908 | 0.78 | NOS3 (0.47) | MAPTNPC1MAPK1RAB9ANPSR1 | |
| SCHEMBL17689388 | 0.77 | MAPT (0.62) | MAPTNPC1MAPK1RAB9ANPSR1 | |
| SCHEMBL27590572 | 0.74 | SIRT2 (0.44) | MAPTNPC1MAPK1RAB9ANPSR1 | |
| SCHEMBL18000472 | 0.74 | MAPT (0.49) | MAPTNPC1MAPK1RAB9ANPSR1 | |
| SCHEMBL16690277 | 0.74 | MAPT (0.48) | MAPTNPC1MAPK1RAB9ANPSR1 | |
| SCHEMBL2676126 | 0.73 | NOS3 (0.44) | MAPTNPC1MAPK1RAB9AL3MBTL1 | |
| SCHEMBL16690299 | 0.72 | MAPT (0.46) | MAPTNPC1MAPK1RAB9ANPSR1 | |
| SCHEMBL2675035 | 0.71 | HRH3 (0.47) | ALDH1A1GAANOS3NOS1MEN1 | |
| SCHEMBL2674973 | 0.71 | ALDH1A1 (0.47) | MAPTNPC1MAPK1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513247-A4 | SIDE CHAIN COPOLYMERS EXHIBITING NONLINEAR OPTICAL RESPONSE | — | 1993-02-03 | — | — | EP | disclosed |
| EP-0513247-A1 | SIDE CHAIN COPOLYMERS EXHIBITING NONLINEAR OPTICAL RESPONSE | HOECHST CELANESE CORPORATION (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5044725-A | Polymeric thin film waveguide media | HOECHST CELANESE CORP. (US) | 1991-09-03 | — | — | US | disclosed |
| WO-1991012462-A1 | SIDE CHAIN COPOLYMERS EXHIBITING NONLINEAR OPTICAL RESPONSE | HOECHST CELANESE CORPORATION (US) | 1991-08-22 | — | — | WO | disclosed |
| US-5041509-A | Side chain copolymers exhibiting nonlinear optical response | CORNING INCORPORATRED | 1991-08-20 | — | — | US | disclosed |
| US-5002361-A | Polymeric thin film waveguide media | HOECHST CELANESE CORP. (US) | 1991-03-26 | — | — | US | disclosed |