Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483888 | 0.84 | MIF (0.67) | MIFCYP3A4ALDH1A1P2RY6MAPT | |
| Bitoscanate SCHEMBL11598436 | 0.79 | MIF (0.68) | MIFCYP3A4ALDH1A1P2RY6MAPT | |
| SCHEMBL1804955 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1P2RY6MAPT | |
| SCHEMBL9446448 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1P2RY6MAPT | |
| SCHEMBL14305109 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1P2RY6MAPT | |
| SCHEMBL9701237 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1P2RY6MAPT | |
| SCHEMBL30298644 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1P2RY6MAPT | |
| SCHEMBL1020537 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1P2RY6MAPT | |
| SCHEMBL20337 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1P2RY6MAPT | |
| SCHEMBL29609574 | 0.74 | MIF (0.54) | MIFCYP3A4ALDH1A1P2RY6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183653-A | BORONIC ACID ADDUCTS OF METAL DIOXIME COMPLEXES USEFUL IN LABELLING PROTEINS AND OTHER AMINE-CONTAINING COMPOUNDS | E. R. SQUIBB & SONS, INC. (US) | 1993-02-02 | — | — | US | claimed |
| EP-0452858-A2 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INTERNATIONAL B.V. (NL) | 1991-10-23 | — | — | EP | claimed |
| EP-0452858-A2 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INTERNATIONAL B.V. (NL) | 1991-10-23 | — | — | EP | disclosed |