Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147920 | 0.95 | CYP3A4 (0.40) | ALDH1A1SMN1; SMN2TDP1HPGDCYP3A4 | |
| SCHEMBL542562 | 0.89 | CYP3A4 (0.43) | ALDH1A1MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL9623392 | 0.84 | CYP3A4 (0.42) | ALDH1A1MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL406943 | 0.81 | GABRA1 (0.38) | ALDH1A1MEN1POLBKMT2ATDP1 | |
| SCHEMBL10533157 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MEN1POLBKMT2ATDP1 | |
| SCHEMBL908852 | 0.80 | CHUK (0.51) | ALDH1A1SMN1; SMN2TDP1HPGDCYP3A4 | |
| SCHEMBL29510772 | 0.80 | CHUK (0.51) | ALDH1A1SMN1; SMN2TDP1HPGDCYP3A4 | |
| SCHEMBL10780213 | 0.77 | KDM4E (0.42) | ALDH1A1MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL6371515 | 0.77 | KDM4E (0.39) | ALDH1A1POLBSMN1; SMN2TDP1HPGD | |
| SCHEMBL6721254 | 0.77 | KDM4E (0.44) | ALDH1A1MEN1KMT2ATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248555-A | Isocyanate, imine | MITSUBISHI PAPER MILLS LIMITED (JP) | 1993-09-28 | — | — | US | disclosed |