Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747138 | 0.82 | CHRM2 (0.63) | HIF1AEPAS1CHRM2ADRA2ADRD1 | |
| SCHEMBL6184529 | 0.82 | HIF1A (0.49) | HIF1AEPAS1CHRM2ADRA2ADRD1 | |
| SCHEMBL9447031 | 0.76 | CYP1A2 (0.54) | HIF1AEPAS1LMNAALDH1A1CYP2D6 | |
| SCHEMBL17064852 | 0.76 | MAOB (0.53) | SMN1; SMN2ALDH1A1MAOAMAOBTSHR | |
| SCHEMBL30270552 | 0.76 | MAOB (0.53) | SMN1; SMN2ALDH1A1MAOAMAOBTSHR | |
| SCHEMBL8805352 | 0.75 | CHRNB2 (0.59) | HIF1AEPAS1CHRM2ADRA2ADRD1 | |
| SCHEMBL9447106 | 0.74 | CYP2D6 (0.74) | HIF1AKDM4EALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL14220155 | 0.74 | MEN1 (0.56) | HIF1AEPAS1CHRM2ADRA2ADRD1 | |
| SCHEMBL6186299 | 0.73 | HIF1A (0.42) | HIF1AEPAS1CHRM2ADRA2ADRD1 | |
| SCHEMBL15131433 | 0.73 | HIF1A (0.46) | HIF1AEPAS1CHRM2ADRA2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |