Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.44 |
| ▸ | CBFB | Q13951 | 2/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283123 | 0.98 | ALDH1A1 (0.56) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| Ammonia Solution, Strong SCHEMBL27721873 | 0.98 | ALDH1A1 (0.56) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| Ethane SCHEMBL9847468 | 0.96 | ALDH1A1 (0.55) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL20592948 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL187244 | 0.85 | NPC1 (0.57) | ALDH1A1MEN1CASP1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL9256396 | 0.83 | NPC1 (0.55) | ALDH1A1MEN1CASP1KMT2AHTT | |
| SCHEMBL6360170 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL9447104 | 0.81 | NR4A2 (0.58) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL464410 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL1495700 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MEN1CASP1CASP7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178938-C | 1,2-annelated quinoline derivatives | ղɭҩҵ����˾ | 2004-12-08 | — | — | CN | claimed |
| CN-1331693-A | 1,2-annelated quinoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2002-01-16 | — | — | CN | claimed |
| CN-1100414-A | Preparation of pharmaceutical compound containing novel derivative of leukol | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1995-03-22 | — | — | CN | claimed |
| CN-1027368-C | Process for preparing substituted quinoline derivatives | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1995-01-11 | — | — | CN | claimed |
| CN-1035501-A | PROCESS FOR PREPARING SUBSTITUTED QUINOLINE DERIVATIVES | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1989-09-13 | — | — | CN | claimed |
| US-20250115604-A1 | SULFOXIMINE GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2025-04-10 | — | — | US | disclosed |
| US-12157734-B2 | Sulfoximine glycosidase inhibitors | ASCENEURON SA (CH) | 2024-12-03 | — | — | US | disclosed |
| CN-115515956-B | Benzimidazole derivative, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-110770226-B | Sulfoximine glycosidase inhibitors | 阿森纽荣股份公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-108137542-B | Pyridone dicarboxamides as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-115515956-A | Benzimidazole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| US-20220177470-A1 | SULFOXIMINE GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2022-06-09 | — | — | US | disclosed |
| US-5441954-A | Treatment of disorders characterized by increased proliferation and/or abnormal differentiation of cells | JANSSEN PHARMACEUTICA N. V. (BE) | 1995-08-15 | — | — | US | disclosed |
| EP-0371564-B1 | (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1995-07-12 | — | — | EP | disclosed |
| CN-1100414-A | Preparation of pharmaceutical compound containing novel derivative of leukol | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1995-03-22 | — | — | CN | disclosed |
| CN-1027368-C | Process for preparing substituted quinoline derivatives | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1995-01-11 | — | — | CN | disclosed |
| US-5268380-A | Therapy for keratinization in mammals | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-12-07 | — | — | US | disclosed |
| US-5185346-A | Antiandrogenic agents; suppress elimination of retinoids; anticarcinogenic agents | HANSSEN PHARMACEUTICA (BE) | 1993-02-09 | — | — | US | disclosed |
| EP-0371564-A2 | (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-06-06 | — | — | EP | disclosed |
| CN-1035501-A | PROCESS FOR PREPARING SUBSTITUTED QUINOLINE DERIVATIVES | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1989-09-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12157734-B2 | Sulfoximine glycosidase inhibitors | ENGASE, BACE1, GAA | ALDH1A1 862/4885MEN1 4011/4885CASP1 3987/4885 |
| US-20220177470-A1 | SULFOXIMINE GLYCOSIDASE INHIBITORS | ENGASE, BACE1, GAA | ALDH1A1 862/4885MEN1 4011/4885CASP1 3987/4885 |
| US-20250115604-A1 | SULFOXIMINE GLYCOSIDASE INHIBITORS | ENGASE, BACE1, GAA | ALDH1A1 955/4885MEN1 3872/4885CASP1 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.