Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.67 |
| ▸ | GLO1 | Q04760 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.55 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447002 | 0.90 | GLO1 (0.69) | SLC40A1GLO1TDP1AGTR1NFKBIA | |
| SCHEMBL9446973 | 0.84 | SLC40A1 (0.73) | SLC40A1GLO1TDP1AGTR1NFKBIA | |
| SCHEMBL6981081 | 0.81 | SLC40A1 (1.00) | SLC40A1GLO1TDP1AGTR1NFKBIA | |
| SCHEMBL30925586 | 0.81 | SLC40A1 (1.00) | SLC40A1GLO1TDP1AGTR1NFKBIA | |
| SCHEMBL9446954 | 0.81 | SLC40A1 (0.70) | SLC40A1GLO1TDP1AGTR1NFKBIA | |
| SCHEMBL9446961 | 0.80 | MAPT (0.57) | SLC40A1GLO1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9447020 | 0.80 | GLO1 (0.55) | SLC40A1GLO1TDP1AGTR1NFKBIA | |
| SCHEMBL10652944 | 0.79 | SLC40A1 (0.53) | SLC40A1GLO1TDP1KMT2AMEN1 | |
| SCHEMBL13485929 | 0.78 | SLC40A1 (0.92) | SLC40A1GLO1TDP1AGTR1NFKBIA | |
| SCHEMBL9446955 | 0.77 | GLO1 (0.54) | SLC40A1GLO1TDP1AGTR1NFKBIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |