Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CISD2 | Q8N5K1 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL773070 | 0.83 | ALDH1A1 (0.46) | GRM6GRM5ALDH1A1HSD17B10CFTR | |
| SCHEMBL28415491 | 0.82 | KDM4E (0.47) | ALDH1A1HSD17B10CFTRCA12CA1 | |
| SCHEMBL7461675 | 0.81 | ALDH1A1 (0.44) | GRM6GRM5ALDH1A1HSD17B10CFTR | |
| SCHEMBL3987873 | 0.81 | MAPT (0.45) | GRM6GRM5ALDH1A1HSD17B10CFTR | |
| SCHEMBL3982680 | 0.79 | KDM4E (0.41) | GRM6GRM5ALDH1A1HSD17B10CFTR | |
| SCHEMBL7827697 | 0.79 | ALDH1A1 (0.42) | GRM6GRM5ALDH1A1HSD17B10CFTR | |
| SCHEMBL3530996 | 0.79 | ALDH1A1 (0.42) | GRM6GRM5ALDH1A1HSD17B10CFTR | |
| SCHEMBL27474595 | 0.79 | ABL1 (0.45) | GRM6GRM5ALDH1A1HSD17B10CFTR | |
| SCHEMBL9447229 | 0.79 | CA1 (0.41) | GRM6GRM5ALDH1A1CA12CA1 | |
| SCHEMBL31038268 | 0.78 | ALDH1A1 (0.44) | GRM6GRM5ALDH1A1HSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190971-A | SUBSTITUTED DIBENZ-OXA-THIOCINONES, -12-OXIDES AND -12,12-DIOXIDES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |