Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447922 | 1.00 | STS (0.38) | STSPRCPSLC22A1OPRM1TAS1R3 | |
| Hydrochloric Acid SCHEMBL9448076 | 0.99 | STS (0.38) | STSPRCPSLC22A1OPRM1TAS1R3 | |
| Hydrochloric Acid SCHEMBL9448069 | 0.99 | STS (0.38) | STSPRCPSLC22A1OPRM1TAS1R3 | |
| SCHEMBL9448312 | 0.86 | PRCP (0.42) | PRCPSLC22A1OPRM1SIGMAR1HTR1A | |
| SCHEMBL9447918 | 0.86 | SLC22A1 (0.49) | PRCPSLC22A1SIGMAR1CYP11B2 | |
| SCHEMBL9448224 | 0.86 | PRCP (0.36) | STSPRCPSLC22A1OPRM1SIGMAR1 | |
| SCHEMBL9447997 | 0.86 | PRCP (0.36) | STSPRCPSLC22A1OPRM1SIGMAR1 | |
| SCHEMBL9448240 | 0.86 | FADS1 (0.41) | STSPRCPSLC22A1OPRM1TAS1R3 | |
| SCHEMBL9448258 | 0.85 | SRD5A1 (0.39) | STS | |
| SCHEMBL9448251 | 0.85 | SRD5A1 (0.39) | STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0461353-A1 | Biogenic amine uptake inhibitors | ABBOTT LABORATORIES (US) | 1991-12-18 | — | — | EP | disclosed |