Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994607 | 0.87 | TSHR (0.73) | TSHRGABRA1GABRB2KDM4EL3MBTL1 | |
| SCHEMBL28416841 | 0.85 | TSHR (0.53) | TSHRGABRA1GABRB2KDM4EL3MBTL1 | |
| SCHEMBL1972902 | 0.84 | TSHR (0.52) | TSHRGABRA1GABRB2KDM4EL3MBTL1 | |
| SCHEMBL3176963 | 0.83 | TSHR (0.56) | TSHRGABRA1GABRB2KDM4EL3MBTL1 | |
| Hydrogen Peroxide SCHEMBL3675725 | 0.82 | TSHR (0.74) | TSHRGABRA1GABRB2KDM4EL3MBTL1 | |
| SCHEMBL20583953 | 0.82 | TSHR (0.43) | TSHRGABRA1GABRB2TRPA1TAAR1 | |
| SCHEMBL14864537 | 0.81 | TSHR (0.43) | TSHRGABRA1GABRB2TAAR1 | |
| SCHEMBL29034985 | 0.80 | GPR84 (0.44) | TSHRTRPA1LMNA | |
| SCHEMBL9621456 | 0.80 | TSHR (0.64) | TSHRGABRA1GABRB2KDM4EL3MBTL1 | |
| SCHEMBL6682973 | 0.80 | TSHR (0.64) | TSHRGABRA1GABRB2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290911-A | Forming polymers by catalytic oxidative coupling | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1994-03-01 | — | — | US | claimed |
| CN-113929866-B | Modified resin and resin composition | 旭化成株式会社 | 2023-07-07 | — | — | CN | disclosed |
| US-11192853-B2 | Separation method and method for producing isocyanate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2021-12-07 | — | — | US | disclosed |
| EP-2641896-B1 | SEPARATION METHOD | ASAHI CHEMICAL IND (JP) | 2020-10-14 | — | — | EP | disclosed |
| EP-2626345-B1 | SEPARATION METHOD AND METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2019-01-16 | — | — | EP | disclosed |
| CN-105358602-B | modified resin and resin composition | 旭化成株式会社 | 2018-12-04 | — | — | CN | disclosed |
| US-9950273-B2 | Method of separation | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2018-04-24 | — | — | US | disclosed |
| US-20180105489-A1 | Separation Method and Method for Producing Isocyanate | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-04-19 | — | — | US | disclosed |
| US-9884810-B2 | Separation method and method for producing isocyanate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2018-02-06 | — | — | US | disclosed |
| CN-107629183-A | Modified resin and resin combination | 旭化成株式会社 | 2018-01-26 | — | — | CN | disclosed |
| EP-0729463-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0402481-B1 | PRODUCTION OF POLYARYLENE THIOETHER | PROD DEV RES INST (JP) | 1995-10-25 | — | — | EP | disclosed |
| WO-1995014012-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |
| WO-1995014011-A2 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |
| US-5290911-A | Forming polymers by catalytic oxidative coupling | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1994-03-01 | — | — | US | disclosed |
| US-5153305-A | From diaryl disulfide; mild conditions using organometallic catalyst | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1992-10-06 | — | — | US | disclosed |
| US-4983720-A | Process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0402481-A1 | PRODUCTION OF POLYARYLENE THIOETHER | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1990-12-19 | — | — | EP | disclosed |
| US-4931542-A | Process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0281036-A2 | A process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192853-B2 | Separation method and method for producing isocyanate | IDH3A, IDH3B, CA9 | TSHR 4739/4885GABRA1 2967/4885GABRB2 2372/4885 |
| US-20180105489-A1 | Separation Method and Method for Producing Isocyanate | IDH3A, IDH3B, CA9 | TSHR 4739/4885GABRA1 2967/4885GABRB2 2372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.