Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10835686 | 0.80 | ADRA1B (0.58) | ADRA1BADRA1A | |
| SCHEMBL9448218 | 0.78 | SRD5A1 (0.58) | — | |
| SCHEMBL9448222 | 0.78 | SRD5A1 (0.58) | — | |
| SCHEMBL9448145 | 0.78 | SRD5A1 (0.58) | — | |
| SCHEMBL9448135 | 0.78 | SRD5A1 (0.58) | — | |
| SCHEMBL9448141 | 0.78 | SRD5A1 (0.58) | — | |
| SCHEMBL8127872 | 0.76 | ADRA1B (0.66) | ADRA1BADRA1A | |
| SCHEMBL7852402 | 0.76 | ADRA1B (0.66) | ADRA1BADRA1A | |
| Hydrochloric Acid SCHEMBL8129441 | 0.75 | ADRA1B (0.65) | ADRA1BADRA1A | |
| Hydrochloric Acid SCHEMBL8139060 | 0.75 | ADRA1B (0.65) | ADRA1BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0461353-A1 | Biogenic amine uptake inhibitors | ABBOTT LABORATORIES (US) | 1991-12-18 | — | — | EP | disclosed |