Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521153 | 0.68 | BRD4 (0.41) | CYP1A2CYP2D6 | |
| SCHEMBL9448099 | 0.68 | KDM4E (0.35) | — | |
| SCHEMBL9548986 | 0.63 | KDM4E (0.38) | — | |
| SCHEMBL769033 | 0.63 | ALDH1A1 (0.31) | — | |
| SCHEMBL9348922 | 0.60 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL1464992 | 0.59 | ALDH1A1 (0.36) | — | |
| SCHEMBL16042631 | 0.58 | RAB9A (0.36) | HSP90AB1 | |
| SCHEMBL10753396 | 0.58 | — | — | |
| SCHEMBL15828711 | 0.58 | ALDH1A1 (0.34) | CYP1A2CYP2D6 | |
| SCHEMBL30507899 | 0.58 | ADORA1 (0.40) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0461353-A1 | Biogenic amine uptake inhibitors | ABBOTT LABORATORIES (US) | 1991-12-18 | — | — | EP | disclosed |