Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.37 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448190 | 0.87 | CYP19A1 (0.43) | CYP19A1NPY5RGRIN2BGRIN1CYP24A1 | |
| SCHEMBL9448276 | 0.76 | GRIN2B (0.43) | NPY5RGRIN2BGRIN1TRPV1SLC6A9 | |
| SCHEMBL9448244 | 0.76 | HTR2C (0.40) | CYP19A1PPARD | |
| SCHEMBL9448318 | 0.76 | FNTA (0.35) | NPY5RTRPV1SLC6A9 | |
| SCHEMBL9447995 | 0.75 | NPY5R (0.41) | CYP19A1NPY5RGRIN2BGRIN1CYP24A1 | |
| SCHEMBL9448423 | 0.75 | NPY5R (0.43) | CYP19A1NPY5RGRIN2BGRIN1CYP24A1 | |
| SCHEMBL9448390 | 0.75 | CYP19A1 (0.42) | CYP19A1NPY5RGRIN2BGRIN1CYP24A1 | |
| SCHEMBL9448017 | 0.73 | TRPV1 (0.35) | TRPV1PPARD | |
| SCHEMBL9448186 | 0.72 | NPY5R (0.46) | NPY5RGRIN2BGRIN1TRPV1SLC6A9 | |
| SCHEMBL9448182 | 0.72 | NPY5R (0.46) | NPY5RGRIN2BGRIN1TRPV1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0461353-A1 | Biogenic amine uptake inhibitors | ABBOTT LABORATORIES (US) | 1991-12-18 | — | — | EP | disclosed |