SCHEMBL94483

SCHEMBL94483

Nc1ccc(N)c(-c2cccc3ccccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
HSD17B10 Q99714 5/20 0.50
HPGD P15428 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 2/20 0.50
CYP3A4 P08684 4/20 0.48
TSHR P16473 2/20 0.48
KEAP1 Q14145 2/20 0.48
CTDSP1 Q9GZU7 1/20 0.44
PRKCZ Q05513 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
TP53 P04637 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
NFE2L2 Q16236 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3989714 0.86 PTPRC (0.57) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL31530764 0.86 PTPRC (0.57) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL2563152 0.86 CA12 (0.47) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL2453081 0.85 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL49880 0.84 CA12 (0.46) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL22517386 0.83 MCL1 (0.47) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL30909419 0.83 MCL1 (0.47) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL22517291 0.81 CYP3A4 (0.45) ALDH1A1HSD17B10HPGDCYP3A4TSHR
SCHEMBL1011515 0.81 MAOB (0.50) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL11353498 0.81 ESR1 (0.48) ALDH1A1HSD17B10HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535764-A Low-odor plastic film material and preparation process thereof 安徽海铭塑业有限公司 2023-08-04 CN claimed
CN-110527268-A A kind of ageing-resistant cracking resistance macromolecule CABLE MATERIALS and preparation method thereof JING FENG CABLE GROUP CO LTD 2019-12-03 CN claimed
CN-110229455-A A kind of high impact modified polystyrene air-conditioning internal machine case material and preparation method thereof 宜宾天原集团股份有限公司 2019-09-13 CN claimed
CN-108047703-A A kind of preparation method of high-strength temperature-resistant roving glass fiber/6/ nylon 66 composite material of nylon 绵阳鸿琪新材料科技有限公司 2018-05-18 CN claimed
CN-107022125-A A kind of rubber composition is with vulcanizing rubber and its preparation method and application 中国石油化工股份有限公司 2017-08-08 CN claimed
CN-104672999-A Weather-proof metallic paint material and preparation method thereof CANHIGH ENGINEERING CO LTD 2015-06-03 CN claimed
CN-103666210-A Copper-based coating made of epoxy modified alkyd resin JIANGSU PAQINI COPPER INDUSTRY CO LTD 2014-03-26 CN claimed
CN-103059377-A Plastic pipe preparation method JIANGSU JINBO NEW MATERIALS TECHNOLOGY CO LTD 2013-04-24 CN claimed
CN-101348410-B Ethylene apparatus caustic wash tower butter inhibitor and use method thereof BEIJING SBL SCIENCE AND TECHNOLOGY DEV CO LTD 2011-03-23 CN claimed
CN-100589212-C Spring cable YUANDONG CABLE CO LTD 2010-02-10 CN claimed
CN-101074315-A Production of high-specific weight resin ZHANG FARAO (CN) 2007-11-21 CN claimed
WO-2004018569-A1 METHOD FOR PRODUCING ADDITIVE CARBON BLACK COLUMBIAN CHEMICALS COMPANY (US) 2004-03-04 WO claimed
EP-1325069-A1 THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS,SECONDARY AMINES, AND LACTONES Uniroyal Chemical Company, Inc. (US) 2003-07-09 EP claimed
US-6569927-B1 Oxidation resistance; synergistic mixtures UNIROYAL CHEMICAL COMPANY, INC. 2003-05-27 US claimed
WO-2002031038-A1 THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS, SECONDARY AMINES, AND LACTONES UNIROYAL CHEMICAL COMPANY, INC. (US) 2002-04-18 WO claimed
EP-1129133-A1 THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS, SECONDARY AMINES, AND THIOETHERS UNIROYAL CHEMICAL COMPANY, Inc. (US) 2001-09-05 EP claimed
US-6277907-B1 STABILIZING THERMOPLASTIC RESINS AGAINST OXIDATIVE DEGRADATION UNIROYAL CHEMICAL COMPANY, INC. 2001-08-21 US claimed
WO-2000027913-A1 THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS, SECONDARY AMINES, AND THIOETHERS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-05-18 WO claimed
WO-1999023154-A1 THERMOPLASTIC RESINS STABILIZED BY BLENDS OF DITHIOCARBAMATES AND AMINES OR PHENOLS UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-05-14 WO claimed
CN-1095392-A Foamed coating for fabric liner JIN AO EMULSION PRODUCTS CO LT (CN) 1994-11-23 CN claimed