SCHEMBL3989714

SCHEMBL3989714

Nc1ccc(-c2ccc(N)cc2-c2cccc3ccccc23)c(-c2cccc3ccccc23)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 2/20 0.57
ALDH1A1 P00352 9/20 0.52
HPGD P15428 6/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
APAF1 O14727 2/20 0.52
LMNA P02545 2/20 0.52
TDP2 O95551 1/20 0.52
NSD2 O96028 1/20 0.52
PLA2G1B P04054 1/20 0.52
POLB P06746 1/20 0.52
CTSL P07711 1/20 0.52
ALOX12 P18054 1/20 0.52
PLCG1 P19174 1/20 0.52
CTSS P25774 1/20 0.52
NPY1R P25929 1/20 0.52
S100A4 P26447 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31530764 1.00 PTPRC (0.57) PTPRCALDH1A1HPGDMEN1KMT2A
SCHEMBL49881 0.91 PRKCZ (0.54) PTPRCALDH1A1HPGDMEN1KMT2A
SCHEMBL29437711 0.89 PRKCZ (0.56) PTPRCALDH1A1HPGDMEN1KMT2A
SCHEMBL1668913 0.89 PRKCZ (0.56) PTPRCALDH1A1HPGDMEN1KMT2A
SCHEMBL26021771 0.89 CDK4 (0.50) PTPRCALDH1A1HPGDMEN1KMT2A
SCHEMBL2453081 0.86 ALDH1A1 (0.50) PTPRCALDH1A1HPGDMEN1KMT2A
SCHEMBL94483 0.86 ALDH1A1 (0.50) PTPRCALDH1A1HPGDMEN1KMT2A
Benz(B)Anthracene SCHEMBL27861166 0.85 PRKCZ (0.51) PTPRCALDH1A1HPGDMEN1KMT2A
SCHEMBL4595260 0.84 ALDH1A1 (0.47) PTPRCALDH1A1HPGDMEN1KMT2A
SCHEMBL20749398 0.82 PTPRC (0.77) PTPRCALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1997814-B1 Electronic Device Including a Buffer Layer Comprising A Functionalized Metal Nanoparticle SAMSUNG ELECTRONICS CO LTD (KR) 2016-02-10 EP claimed
EP-1997814-A1 Functionalized Metal Nanoparticle, Buffer Layer Including the Same and Electronic Device Including the Buffer Layer Samsung Electronics Co., Ltd. (KR) 2008-12-03 EP claimed
EP-3039487-A1 MOLECULAR GLASS MIXTURES FOR ORGANIC ELECTRONICS APPLICATIONS Molaire Consulting LLC (US) 2016-07-06 EP disclosed
EP-1997814-B1 Electronic Device Including a Buffer Layer Comprising A Functionalized Metal Nanoparticle SAMSUNG ELECTRONICS CO LTD (KR) 2016-02-10 EP disclosed
WO-2014127085-A1 BUCKLED ORGANIC LIGHT EMITTING DIODE FOR LIGHT EXTRACTION WITHOUT BLURRING UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2014-08-21 WO disclosed
WO-2014004469-A2 BUCKLED ORGANIC LIGHT EMITTING DIODE FOR LIGHT EXTRACTION UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2014-01-03 WO disclosed
WO-2009066791-A1 MULTICOLOR DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-05-28 WO disclosed
EP-1997814-A1 Functionalized Metal Nanoparticle, Buffer Layer Including the Same and Electronic Device Including the Buffer Layer Samsung Electronics Co., Ltd. (KR) 2008-12-03 EP disclosed
EP-1885818-A1 ELECTROLUMINESCENT DEVICE Ciba Specialty Chemicals Holding Inc. (CH) 2008-02-13 EP disclosed
WO-2006128800-A1 ELECTROLUMINESCENT DEVICE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-07 WO disclosed
US-20050236976-A1 Organic electroluminescent device RITDISPLAY CORPORATION (TW) 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050236976-A1 Organic electroluminescent device ARL1, OR10J3, MCOLN1 PTPRC 4712/4885ALDH1A1 593/4885HPGD 4794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.