SCHEMBL9448441

SCHEMBL9448441

C1=CC2=C(CC1)Cc1ccccc1N2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
NPC1 O15118 2/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
AHR P35869 1/20 0.44
PDK2 Q15119 1/20 0.44
HSP90AA1 P07900 1/20 0.44
THRB P10828 1/20 0.44
HK1 P19367 1/20 0.44
MAPK1 P28482 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44
GALK1 P51570 1/20 0.44
BLM P54132 1/20 0.44
HKDC1 Q2TB90 1/20 0.44
MAPK13 O15264 1/20 0.39
MAPK12 P53778 1/20 0.39
MAPK11 Q15759 1/20 0.39
MAPK14 Q16539 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL26977357 0.98 MAPT (0.43) MAPTNPC1KDM4EMEN1KMT2A
SCHEMBL20218953 0.86 NPC1 (0.47) MAPTNPC1KDM4EMEN1KMT2A
SCHEMBL8625976 0.75 ALOX15 (0.49) MAPTNPC1KDM4EMEN1KMT2A
SCHEMBL19393672 0.74 MAPT (0.43) MAPTNPC1KDM4EMEN1KMT2A
SCHEMBL20345802 0.71 NPC1 (0.36) MAPTNPC1KDM4EMEN1KMT2A
SCHEMBL8663476 0.69 CYP1A2 (0.34) CYP1A2
SCHEMBL21335976 0.69 GAA (0.33) MAPTNPC1MEN1KMT2AMAPK13
SCHEMBL20707948 0.69
SCHEMBL23572251 0.69 NPC1 (0.44) MAPTNPC1KDM4EMEN1KMT2A
SCHEMBL13772803 0.69 NPC1 (0.53) MAPTNPC1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0536283-A4 RESERVOIR CHEMICAL SENSORS WITH OPTIONAL REMOVABLE RESERVOIR CELLS 1993-05-26 EP claimed
EP-0536283-A1 RESERVOIR CHEMICAL SENSORS WITH OPTIONAL REMOVABLE RESERVOIR CELLS FIBERCHEM, INC. (US) 1993-04-14 EP claimed
US-5116759-A Reservoir chemical sensors FIBERCHEM INC. (US) 1992-05-26 US claimed
WO-1992000515-A1 RESERVOIR CHEMICAL SENSORS WITH OPTIONAL REMOVABLE RESERVOIR CELLS FIBERCHEM, INC. (US) 1992-01-09 WO claimed
EP-4717753-A2 LUBRICANT COMPOSITIONS FOR DIRECT INJECTION ENGINES The Lubrizol Corporation (US) 2026-04-01 EP disclosed
EP-3878933-B1 LUBRICANT COMPOSITIONS FOR DIRECT INJECTION ENGINES LUBRIZOL CORP (US) 2025-11-05 EP disclosed
EP-4314211-B1 ZINC FREE LUBRICATING COMPOSITIONS AND METHODS OF USING THE SAME LUBRIZOL CORP (US) 2025-10-15 EP disclosed
US-20250263626-A1 ZINC FREE LUBRICATING COMPOSITIONS AND METHODS OF USING THE SAME THE LUBRIZOL CORPORATION (US) 2025-08-21 US disclosed
US-12305141-B2 Zinc free lubricating compositions and methods of using the same THE LUBRIZOL CORPORATION (US) 2025-05-20 US disclosed
US-20240199974-A1 Zinc Free Lubricating Compositions And Methods Of Using The Same THE LUBRIZOL CORPORATION (US) 2024-06-20 US disclosed
EP-4314211-A1 ZINC FREE LUBRICATING COMPOSITIONS AND METHODS OF USING THE SAME The Lubrizol Corporation (US) 2024-02-07 EP disclosed
EP-3778837-B1 USE OF LUBRICANT COMPOSITIONS FOR DIRECT INJECTION ENGINES LUBRIZOL CORP (US) 2024-01-17 EP disclosed
US-20140187458-A1 Lubricating Composition With Improved TBN Retention THE LUBRIZOL CORPORATION (US) 2014-07-03 US disclosed
CN-103703114-A Lubricating composition with improved tbn retention LUBRIZOL CORP 2014-04-02 CN disclosed
WO-2012166781-A1 LUBRICATING COMPOSITION WITH IMPROVED TBN RETENTION THE LUBRIZOL CORPORATION (US) 2012-12-06 WO disclosed
EP-1744212-A2 Photosensitive composition Fuji Photo Film Co., Ltd. (JP) 2007-01-17 EP disclosed
EP-0536283-A4 RESERVOIR CHEMICAL SENSORS WITH OPTIONAL REMOVABLE RESERVOIR CELLS 1993-05-26 EP disclosed
EP-0536283-A1 RESERVOIR CHEMICAL SENSORS WITH OPTIONAL REMOVABLE RESERVOIR CELLS FIBERCHEM, INC. (US) 1993-04-14 EP disclosed
US-5116759-A Reservoir chemical sensors FIBERCHEM INC. (US) 1992-05-26 US disclosed
WO-1992000515-A1 RESERVOIR CHEMICAL SENSORS WITH OPTIONAL REMOVABLE RESERVOIR CELLS FIBERCHEM, INC. (US) 1992-01-09 WO disclosed