SCHEMBL8663476

SCHEMBL8663476

C1=CC2=C(CC1)Cc1ccccc1C2

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
DRD2 P14416 1/20 0.33
DRD1 P21728 1/20 0.33
DRD4 P21917 1/20 0.33
DRD5 P21918 1/20 0.33
DRD3 P35462 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520167 0.88 CYP2A6 (0.41) CYP1A2CYP2A6DRD2DRD1DRD4
SCHEMBL3840834 0.88 CYP2A6 (0.41) CYP1A2CYP2A6DRD2DRD1DRD4
SCHEMBL8625976 0.77 ALOX15 (0.49)
SCHEMBL8664552 0.77
SCHEMBL25834858 0.75 DRD2 (0.33) CYP1A2DRD2DRD1DRD4DRD5
SCHEMBL5851201 0.72 MAOA (0.42) CYP1A2CYP2A6MAOAMAOB
SCHEMBL22362502 0.72 CHRM2 (0.39) CYP1A2CYP2A6DRD1DRD3MAOA
SCHEMBL315443 0.72 MAOA (0.48) MAOAMAOB
SCHEMBL25924715 0.72 ACHE (0.32)
SCHEMBL4652407 0.71 TSHR (0.37) CYP1A2CYP2A6DRD2DRD1DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4039776-A2 POLYMERISABLE LC MATERIAL AND POLYMER FILM Merck Patent GmbH (DE) 2022-08-10 EP disclosed
US-5808154-A Process for the production of an aromatic hydrazo compound TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-15 US disclosed
EP-0391606-B1 Process for the production of an aromatic hydrazo compound TOYO INK MFG CO (JP) 1995-07-05 EP disclosed