Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448472 | 0.93 | PTGS1 (0.41) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL9007849 | 0.85 | PTGS1 (0.59) | PTGS1GSTK1GLO1 | |
| SCHEMBL19282334 | 0.83 | KMT2A (0.40) | PTGS1GSTK1GLO1KMT2AMMP2 | |
| SCHEMBL19282338 | 0.83 | KMT2A (0.40) | PTGS1GSTK1GLO1KMT2AMMP2 | |
| SCHEMBL9448659 | 0.82 | PTGS1 (0.44) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL9448531 | 0.80 | DPP4 (0.34) | DPP4DPP8DPP9KMT2AMMP2 | |
| SCHEMBL10940525 | 0.80 | CTSL (0.46) | KMT2A | |
| SCHEMBL10940533 | 0.80 | CTSL (0.46) | KMT2A | |
| SCHEMBL11306085 | 0.80 | ACE (0.47) | KMT2A | |
| SCHEMBL11306078 | 0.80 | ACE (0.47) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536231-A1 | A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES, COMPOUNDS OBTAINED FROM SAID PROCESS AND AN INTERMEDIATE USEFUL FOR THE PREPARATION THEREOF. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | disclosed |