Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 3/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448511 | 0.82 | DPP4 (0.42) | DPP4DPP8DPP9KMT2AALOX15 | |
| SCHEMBL9448488 | 0.80 | PTGS1 (0.40) | DPP4DPP8DPP9KMT2AGPR139 | |
| SCHEMBL9448472 | 0.73 | PTGS1 (0.41) | DPP4DPP8DPP9GPR139LTA4H | |
| SCHEMBL10943024 | 0.70 | KMT2A (0.47) | KMT2AMMEECE1GPR139MMP2 | |
| SCHEMBL23154641 | 0.69 | GPR139 (0.45) | KMT2AGPR139 | |
| SCHEMBL28769012 | 0.69 | GPR139 (0.45) | KMT2AGPR139 | |
| SCHEMBL28767091 | 0.69 | GPR139 (0.39) | KMT2AGPR139LTA4H | |
| SCHEMBL28769015 | 0.69 | GPR139 (0.38) | KMT2AECE1GPR139 | |
| SCHEMBL29744501 | 0.69 | CTSC (0.50) | MMELTA4H | |
| Hydrochloric Acid SCHEMBL28767111 | 0.69 | GPR139 (0.44) | KMT2AGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536231-A1 | A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES, COMPOUNDS OBTAINED FROM SAID PROCESS AND AN INTERMEDIATE USEFUL FOR THE PREPARATION THEREOF. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | disclosed |