Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 8/20 | 0.40 |
| ▸ | NPY1R | P25929 | 5/20 | 0.40 |
| ▸ | NPY2R | P49146 | 4/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | TFPI | P10646 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30974097 | 0.89 | GLO1 (0.41) | KEAP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL14028314 | 0.88 | NOD1 (0.41) | KEAP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31349358 | 0.88 | NPY4R (0.40) | KEAP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31031613 | 0.88 | NOD1 (0.43) | KEAP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL17955408 | 0.88 | NPY4R (0.44) | KEAP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13496859 | 0.87 | NPY4R (0.40) | KEAP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7394659 | 0.87 | NPY4R (0.40) | KEAP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL17732657 | 0.84 | NPY4R (0.40) | BMP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29642947 | 0.84 | TFPI (0.44) | KEAP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30521941 | 0.83 | OPRL1 (0.43) | NPY4RNPY1RNPY2RNPY5ROPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522081-A4 | INHIBITION OF DISEASE ASSOCIATED WITH IMMUNODEFICIENCY VIRUS INFECTION | — | 1993-06-16 | — | — | EP | disclosed |
| EP-0522081-A1 | INHIBITION OF DISEASE ASSOCIATED WITH IMMUNODEFICIENCY VIRUS INFECTION | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991015224-A1 | INHIBITION OF DISEASE ASSOCIATED WITH IMMUNODEFICIENCY VIRUS INFECTION | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-17 | — | — | WO | disclosed |