Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.40 |
| ▸ | ITGAV | P06756 | 14/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 14/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448586 | 1.00 | TPSAB1 (0.46) | TPSAB1ITGB3ITGAVITGB5 | |
| Novexatin SCHEMBL29715903 | 0.89 | TPSAB1 (0.50) | TPSAB1 | |
| SCHEMBL14906469 | 0.89 | TPSAB1 (0.50) | TPSAB1 | |
| SCHEMBL29726666 | 0.89 | ITGB3 (0.54) | ITGB3ITGAVITGB5 | |
| SCHEMBL29568996 | 0.85 | ITGB3 (0.51) | ITGB3ITGAVITGB5 | |
| SCHEMBL8321039 | 0.84 | ITGB3 (0.56) | ITGB3ITGAVITGB5 | |
| SCHEMBL4405241 | 0.84 | TPSAB1 (0.46) | TPSAB1 | |
| SCHEMBL24253221 | 0.83 | ITGB3 (0.49) | ITGB3ITGAVITGB5 | |
| SCHEMBL29568988 | 0.82 | TPSAB1 (0.48) | TPSAB1ITGB3 | |
| SCHEMBL29569477 | 0.82 | TPSAB1 (0.48) | TPSAB1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522081-A4 | INHIBITION OF DISEASE ASSOCIATED WITH IMMUNODEFICIENCY VIRUS INFECTION | — | 1993-06-16 | — | — | EP | disclosed |
| EP-0522081-A1 | INHIBITION OF DISEASE ASSOCIATED WITH IMMUNODEFICIENCY VIRUS INFECTION | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991015224-A1 | INHIBITION OF DISEASE ASSOCIATED WITH IMMUNODEFICIENCY VIRUS INFECTION | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-17 | — | — | WO | disclosed |