Phosphoric Acid

Phosphoric Acid

SCHEMBL9448682

O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.[Ti]

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.50
SLC34A1 Q06495 1/20 0.46
FDPS P14324 2/20 0.42
BLM P54132 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MMP2 P08253 1/20 0.42
THRB P10828 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TYMS P04818 1/20 0.36
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL11399479 1.00 CA2 (0.50) CA2SLC34A1FDPSBLMTDP1
Phosphoric Acid SCHEMBL27460 1.00
Phosphoric Acid SCHEMBL1255247 1.00 CA2 (0.50) CA2SLC34A1FDPSBLMTDP1
Phosphoric Acid SCHEMBL12803439 0.94
Phosphoric Acid SCHEMBL20358160 0.94
Phosphoric Acid SCHEMBL25407717 0.94
Phosphoric Acid SCHEMBL6046990 0.94
Phosphoric Acid SCHEMBL23189470 0.94
Phosphoric Acid SCHEMBL2867178 0.94
Phosphoric Acid SCHEMBL8421044 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4806517-A Method for making pelleted phosphated catalysts derived from group IVB transition metal oxides and catalysts thus prepared TEXACO INC. (US) 1989-02-21 US claimed
US-4588842-A 4B OXIDE TREATED WITH PHOSPHORUS COMPOUND TEXACO INC. (US) 1986-05-13 US claimed
US-4578518-A Catalytic (calcined catalyst and) preparation of linear polyethylenepolyamines (therewith) TEXACO INC. (US) 1986-03-25 US claimed
EP-0115138-A1 Regenerative process for the preparation of linear polyethylenepolyamines using a supported catalyst TEXACO DEVELOPMENT CORPORATION (US) 1984-08-08 EP claimed
US-20160223927-A1 POLYESTER RESIN COMPOSITION FOR ELECTROPHOTOGRAPHIC TONER, AND ELECTROPHOTOGRAPHIC TONER DIC CORPORATION (JP) 2016-08-04 US disclosed
US-5231230-A Metatungstate and metal oxide catalysts for condensation of ethyleneddiamine with ethanolamine UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-07-27 US disclosed
US-5225598-A SELECTIVE PRODUCTION OF LINEAR PENTAETHYLENEHEXAMINE AND HYDROXYETHYLDIETHYLENETRIAMINE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-07-06 US disclosed
US-5225600-A Reaction of alkanolamine with alkyleneamine or another alkanol amine UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-07-06 US disclosed
US-5220071-A Continuous process of condensing ethylenediamine and a N,N- or N,N'-bis(2-hydroxyethyl)ethylenediamine using a catalyst of a metatungstate and a Group 4 metal oxide UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-06-15 US disclosed
US-5214213-A Condensing ethylenediamine and diethanolamine using a titanium dioxide-metatungstate catalyst UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-05-25 US disclosed
US-5210306-A Making polyalkylene polyamines by catalytic condensation of alkanolamines or alkylene glycols with alkyleneamines or more alkanolamines using metatungstate catalysts with phosphorus-free promoters UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-05-11 US disclosed
US-5202489-A High-surface area Group 4B metal oxide condensation catalysts for making polyalkylenepolyamine compounds using amines and ammonia as reactants UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-04-13 US disclosed
US-5202492-A Producing polyalkylene polyamines UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-04-13 US disclosed
US-5166415-A Catalytic condensation of ethylenediamine and ethanolamine UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-11-24 US disclosed
US-5101074-A Acid catalysts for making alkyleneamines UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-03-31 US disclosed
US-4983736-A Amines catalysis using metallic polyphosphate condensation catalysts having a condensed structure UNION CARBIDE CHEMICALS AND PLASTIC COMPANY INC. (US) 1991-01-08 US disclosed
US-4806517-A Method for making pelleted phosphated catalysts derived from group IVB transition metal oxides and catalysts thus prepared TEXACO INC. (US) 1989-02-21 US disclosed
US-4654261-A DISPERSION OF WHITE PIGMENT AND TETRACRYLATE ESTER OF PENTAERYTHRITHOL ALKYLENE OXIDE ADDUCT FUJI PHOTO FILM CO., LTD. 1987-03-31 US disclosed