Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13412924 | 0.88 | ALDH1A1 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL13936459 | 0.84 | ALDH1A1 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL17995311 | 0.84 | ALDH1A1 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL24633781 | 0.84 | ALDH1A1 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL16446118 | 0.84 | ALDH1A1 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL23901564 | 0.84 | ALDH1A1 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL21555767 | 0.83 | ALDH1A1 (0.51) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL14655692 | 0.83 | ALDH1A1 (0.51) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL28777999 | 0.83 | ALDH1A1 (0.51) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL2912589 | 0.83 | CASP1 (0.60) | ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1309702-C | Synthesis method of kynureninase specificity inhibitor-L-methoxybenzoyl alanine | SHANGHAI INST ORGANIC CHEM (CN) | 2007-04-11 | — | — | CN | disclosed |
| CN-1752068-A | The synthetic method of the specific inhibitor L-O-methoxy benzoyl L-Ala of kynureninase | SHANGHAI INST ORGANIC CHEM (CN) | 2006-03-29 | — | — | CN | disclosed |
| CN-1752068-A | The synthetic method of the specific inhibitor L-O-methoxy benzoyl L-Ala of kynureninase | SHANGHAI INST ORGANIC CHEM (CN) | 2006-03-29 | — | — | CN | disclosed |
| US-5258398-A | Anticoagulants; platelet aggregation inhibitors | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1993-11-02 | — | — | US | disclosed |