Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643286 | 0.92 | ABCB11 (0.45) | ABCB11HPGDTSHRCYP1A2CYP2C9 | |
| SCHEMBL9642645 | 0.92 | ABCB11 (0.45) | ABCB11HPGDTSHRCYP1A2CYP2C9 | |
| SCHEMBL9643429 | 0.90 | ABCB11 (0.44) | ABCB11ALOX15ALDH1A1GLAMAPK1 | |
| SCHEMBL9643262 | 0.90 | ABCB11 (0.44) | ABCB11ALOX15ALDH1A1GLAMAPK1 | |
| SCHEMBL9642891 | 0.89 | ABCB11 (0.50) | ABCB11HPGDTSHRCYP1A2CYP2C9 | |
| SCHEMBL9643337 | 0.87 | ABCB11 (0.70) | ABCB11HPGDTSHRCYP1A2CYP2C9 | |
| SCHEMBL9644133 | 0.87 | ABCB11 (0.70) | ABCB11HPGDCYP1A2CYP2C9HIF1A | |
| SCHEMBL9642288 | 0.85 | ABCB11 (0.68) | ABCB11HPGDCYP1A2CYP2C9HIF1A | |
| SCHEMBL9642820 | 0.85 | ABCB11 (0.68) | ABCB11HPGDCYP1A2CYP2C9HIF1A | |
| SCHEMBL24893025 | 0.85 | ABCB11 (0.51) | ABCB11HPGDCYP1A2CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242946-A | Treating herpes Viral infections | BIO-MEGA, INC. (CA) | 1993-09-07 | — | — | US | claimed |
| US-5242946-A | Treating herpes Viral infections | BIO-MEGA, INC. (CA) | 1993-09-07 | — | — | US | disclosed |
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |
| US-4593120-A | Naphthalene-1,4-dicarboxylic acid group | SYNTEX (U.S.A.) INC. (US) | 1986-06-03 | — | — | US | disclosed |