Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPD | P32754 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875333 | 0.87 | KDM4E (0.40) | KDM4ELMNAPOLBSRCALDH1A1 | |
| SCHEMBL11023721 | 0.84 | ALDH1A1 (0.49) | KDM4ELMNAPOLBALDH1A1L3MBTL1 | |
| SCHEMBL11326215 | 0.84 | MEN1 (0.42) | KDM4ELMNAMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL11316683 | 0.83 | SRC (0.36) | KDM4ELMNAPOLBSRCALDH1A1 | |
| SCHEMBL11324790 | 0.83 | KDM4E (0.37) | KDM4ELMNAPOLBSRCALDH1A1 | |
| SCHEMBL11326210 | 0.83 | MAPK1 (0.36) | KDM4ELMNAMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL11125006 | 0.82 | ALDH1A1 (0.44) | KDM4ELMNAMAPK1POLBALDH1A1 | |
| SCHEMBL8345205 | 0.81 | KDM4E (0.30) | KDM4E | |
| SCHEMBL11321360 | 0.80 | KDM4E (0.35) | KDM4ELMNAPOLBSRCALDH1A1 | |
| SCHEMBL11337957 | 0.78 | SRC (0.33) | KDM4EPOLBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227475-A | WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| US-4918183-A | Monoazo dyes, process for their preparation, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| US-4602084-A | Monoazo dyes containing a 4-substituted-2-azo-1,1'-diphenylsulfone component | CIBA-GEIGY CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0040582-B1 | AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1985-03-20 | — | — | EP | disclosed |
| US-4283331-A | FIBER-REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |