Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264914 | 0.89 | PTPN1 (0.52) | PTPN1MDM4TP53CASP3CTSK | |
| SCHEMBL29700028 | 0.88 | PTPN1 (0.56) | PTPN1MDM4TP53CASP3CTSK | |
| SCHEMBL29990051 | 0.88 | PTPN1 (0.56) | PTPN1MDM4TP53CASP3CTSK | |
| SCHEMBL30261676 | 0.88 | PTPN1 (0.53) | PTPN1MDM4TP53 | |
| SCHEMBL29531966 | 0.88 | PTPN1 (0.53) | PTPN1MDM4TP53 | |
| SCHEMBL31589788 | 0.88 | PTPN1 (0.56) | PTPN1MDM4TP53CASP3 | |
| SCHEMBL30153671 | 0.88 | PTPN1 (0.56) | PTPN1MDM4TP53CASP3CTSK | |
| SCHEMBL12206292 | 0.88 | CASP3 (0.50) | MDM4TP53CASP3EPHX2KMT2A | |
| N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL1002861 | 0.88 | MDM4 (0.58) | PTPN1MDM4TP53CASP3KMT2A | |
| N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL120560 | 0.88 | MDM4 (0.58) | PTPN1MDM4TP53CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531443-A4 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0531443-A1 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5079260-A | Side effect reduction; fluorene derivatives | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-01-07 | — | — | US | disclosed |
| WO-1991018596-A1 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | WEITZBERG MOSHE (US) | 1991-12-12 | — | — | WO | disclosed |