Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | SI | P14410 | 6/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840122 | 0.86 | GPR84 (0.59) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL21870764 | 0.86 | GPR84 (0.59) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL9594578 | 0.83 | GPR84 (0.56) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL148211 | 0.82 | MAPT (0.68) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL839703 | 0.80 | GPR84 (0.52) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL7820062 | 0.80 | GPR84 (0.56) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL24123052 | 0.80 | GPR84 (0.67) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL4001470 | 0.79 | GPR84 (0.51) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL15229686 | 0.78 | GPR84 (0.60) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL20551986 | 0.78 | GPR84 (0.61) | GPR84FFAR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229413-A | Nervous system disorders | G. D. SEARLE & CO. (US) | 1993-07-20 | — | — | US | disclosed |
| US-5137910-A | Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders | C.D. SEARLE & CO. (US) | 1992-08-11 | — | — | US | disclosed |