Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SI | P14410 | 2/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840122 | 1.00 | GPR84 (0.59) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL31641721 | 0.89 | GPR84 (0.61) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL20551986 | 0.89 | GPR84 (0.61) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL31000506 | 0.89 | GPR84 (0.61) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL31641611 | 0.89 | GPR84 (0.61) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL31646294 | 0.89 | GPR84 (0.61) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL21870762 | 0.89 | GPR84 (0.61) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL31642552 | 0.89 | GPR84 (0.61) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL31641958 | 0.88 | HTR2A (0.51) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL31642540 | 0.88 | HTR2A (0.51) | GPR84FFAR1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2024-07-02 | — | — | US | disclosed |
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2024-07-02 | — | — | US | disclosed |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-10-29 | — | — | US | disclosed |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | AANAT, AADAT, TPH1 | GPR84 3894/4885FFAR1 3292/4885MEN1 3675/4885 |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | AANAT, AADAT, TPH1 | GPR84 3894/4885FFAR1 3292/4885MEN1 3675/4885 |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | AANAT, TPH1, AADAT | GPR84 3415/4885FFAR1 2270/4885MEN1 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.