SCHEMBL9449674

SCHEMBL9449674

C[C@@H](Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)Cl

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.60
RAB9A P51151 1/20 0.54
LIPE Q05469 15/20 0.54
MAPT P10636 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
BCHE P06276 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30749511 1.00 LMNA (0.60) LMNARAB9ALIPEMAPTNPSR1
SCHEMBL9449464 1.00 LMNA (0.60) LMNARAB9ALIPEMAPTNPSR1
Hydrochloric Acid SCHEMBL9362434 0.99 LMNA (0.59) LMNARAB9ALIPEMAPTNPSR1
Fluazifop-P SCHEMBL29370487 0.89 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop-P SCHEMBL118853 0.89 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL29370478 0.89 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL67403 0.89 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL1010239 0.89 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL1559717 0.89 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop-P SCHEMBL11006621 0.88 LMNA (0.60) LMNARAB9ALIPEMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107382980-B N- [ (dihydrobenzofuran-7-oxy) alkyl ] -2-aryloxyamide derivatives 湖南大学 2020-05-15 CN disclosed
US-5199970-A Preemergence; postemergence; monocotyledonous weeds; moderately toxic ALKALOIDA VEGYESZETI GYAR (HU) 1993-04-06 US disclosed
EP-0426491-A2 Herbicidal, optically active or racemic substituted propionic acid derivatives, herbicide compositions containing them and process for preparing same ALKALOIDA VEGYESZETI GYAR (HU) 1991-05-08 EP disclosed
US-4522647-A Substituted phenoxyalkanediones and their herbicidal method of use ZOECON CORPORATION (US) 1985-06-11 US disclosed
EP-0109483-A1 Substituted phenoxyalkane diones, intermediates for these compounds and the use of phenoxyalkane diones in the control of weeds ZOECON CORPORATION (US) 1984-05-30 EP disclosed