Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347727 | 0.79 | RHEB (0.62) | RHEBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29989576 | 0.79 | RHEB (0.62) | RHEBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9450136 | 0.78 | MEN1 (0.38) | RHEBMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL238441 | 0.77 | CA1 (0.57) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3922552 | 0.76 | NQO2 (0.46) | RHEBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13868223 | 0.76 | NQO2 (0.46) | RHEBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6764470 | 0.73 | RHEB (0.44) | RHEBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9450204 | 0.72 | TUBB4A (0.68) | RHEBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2737345 | 0.72 | NQO2 (0.48) | RHEBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11199118 | 0.72 | NQO2 (0.42) | RHEBTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182282-A | Antiarrhythmia agents | ROUSSEL UCLAF (FR) | 1993-01-26 | — | — | US | disclosed |
| US-5086070-A | 4-BENZYL-1H-INDOLES AND ANTI-ARRTHYMIC USE THEREOF | ROUSSEL UCLAF (FR) | 1992-02-04 | — | — | US | disclosed |