Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16635714 | 0.90 | SLC6A12 (0.40) | KCNQ3KCNQ2KCNQ4KCNQ5SLC6A12 | |
| SCHEMBL18279798 | 0.84 | CHRM2 (0.35) | KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL17008630 | 0.84 | CHRM2 (0.35) | KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL16636351 | 0.81 | HRH3 (0.32) | KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL16636353 | 0.81 | HRH3 (0.32) | KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL10704175 | 0.76 | SLC6A12 (0.45) | KCNQ3KCNQ2KCNQ4KCNQ5SLC6A12 | |
| SCHEMBL4303990 | 0.76 | GRM2 (0.32) | — | |
| SCHEMBL16635971 | 0.75 | EPHX2 (0.34) | — | |
| SCHEMBL7271372 | 0.72 | GABRR1 (0.35) | — | |
| SCHEMBL17237823 | 0.72 | GABRR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5233054-A | Dehydrogenating, brominating the halogen substituted hexa- or tetra-hydrophthalic anhydride in the presence of free radical catalysts | OCCIDENTAL CHEMICAL CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |
| US-5206391-A | Reacting BR2 with halohydrophthalic anhydride, reacting HBR with CL2 to regenerate bromine | OCCIDENTAL CHEMICAL CORPORATION (US) | 1993-04-27 | — | — | US | disclosed |
| US-5049682-A | Halogenation | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0417691-A2 | Process for the preparation of halophthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-03-20 | — | — | EP | disclosed |