Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 1.00 |
| ▸ | CNR1 | P21554 | 5/20 | 1.00 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | PLEC | Q15149 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945045 | 1.00 | CNR2 (1.00) | CNR2CNR1PIM1CLK2CLK4 | |
| SCHEMBL26376123 | 1.00 | CNR2 (1.00) | CNR2CNR1PIM1CLK2CLK4 | |
| SCHEMBL3382611 | 0.88 | CNR2 (0.78) | CNR2CNR1PIM1CLK2CLK4 | |
| SCHEMBL3382608 | 0.88 | CNR2 (0.78) | CNR2CNR1PIM1CLK2CLK4 | |
| SCHEMBL26376128 | 0.85 | CNR2 (0.74) | CNR2CNR1PIM1CLK2CLK4 | |
| SCHEMBL944836 | 0.85 | CNR2 (0.73) | CNR2CNR1PIM1CLK2CLK4 | |
| SCHEMBL944835 | 0.85 | CNR2 (0.73) | CNR2CNR1PIM1CLK2CLK4 | |
| SCHEMBL24194110 | 0.83 | CNR2 (0.70) | CNR2CNR1PIM1CLK2CLK4 | |
| SCHEMBL26376471 | 0.82 | CNR2 (0.80) | CNR2CNR1PIM1CLK2CLK4 | |
| SCHEMBL26376130 | 0.82 | CNR2 (0.93) | CNR2CNR1PIM1CLK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3664795-B1 | CANNABIS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN AND INFLAMMATION RELATED WITH DENTAL PULP AND BONE REGENERATION RELATED TO DENTAL JAW BONE DEFECTS | CANNIBITE BVBA (BE) | 2024-06-19 | — | — | EP | claimed |
| CN-117100863-A | Use of cannabinoid systems and downstream pathways thereof for preventing and/or treating chronic itch | 南方科技大学 | 2023-11-24 | — | — | CN | claimed |
| EP-2211860-B1 | COMBINATION THERAPY FOR REDUCING SIDE EFFECTS USING CANNABINOID RECEPTOR LIGANDS | ABBVIE INC (US) | 2015-04-08 | — | — | EP | claimed |
| US-8044071-B2 | Method for reducing side effects of CB2 receptor agonist therapy using a combination of a selective CB2 receptor agonist and a selective CB1 receptor antagonist | ABBOTT LABORATORIES (US) | 2011-10-25 | — | — | US | claimed |
| EP-4646477-A2 | METHODS AND COMPOSITIONS FOR DISPLAYING PEPTIDE LIBRARIES | Board of Regents, The University of Texas System (US) | 2025-11-12 | — | — | EP | disclosed |
| US-20250027072-A1 | METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2025-01-23 | — | — | US | disclosed |
| EP-4178951-B1 | DEUTERATED AND TRITIATED N-(4,5-DIMETHYLTHIAZOLO-2(3H)-YLIDEN)-2,2,3,3-TETRAMETHYLCYCLOPROPANE-1-CARBOXAMIDE DERIVATIVES AND THEIR USE | HELMHOLTZ ZENTRUM DRESDEN (DE) | 2024-12-11 | — | — | EP | disclosed |
| EP-4441203-A1 | METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS | Board of Regents, The University of Texas System (US) | 2024-10-09 | — | — | EP | disclosed |
| WO-2024148130-A2 | METHODS AND COMPOSITIONS FOR DISPLAYING PEPTIDE LIBRARIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-11 | — | — | WO | disclosed |
| EP-3664795-B1 | CANNABIS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN AND INFLAMMATION RELATED WITH DENTAL PULP AND BONE REGENERATION RELATED TO DENTAL JAW BONE DEFECTS | CANNIBITE BVBA (BE) | 2024-06-19 | — | — | EP | disclosed |
| CN-117100863-A | Use of cannabinoid systems and downstream pathways thereof for preventing and/or treating chronic itch | 南方科技大学 | 2023-11-24 | — | — | CN | disclosed |
| US-20230312493-A1 | DEUTERATED AND TRITIATED N-(4,5-DIMETHYLTHIAZOLO-2(3H)-YLIDEN)-2,2,3,3-TETRAMETHYLCYCLOPROPANE-1-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2023-10-05 | — | — | US | disclosed |
| EP-2222165-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-09-01 | — | — | EP | disclosed |
| EP-2211860-A1 | COMBINATION THERAPY FOR REDUCING SIDE EFFECTS USING CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-08-04 | — | — | EP | disclosed |
| US-20100093814-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-04-15 | — | — | US | disclosed |
| WO-2009067613-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-05-28 | — | — | WO | disclosed |
| US-20090105304-A1 | COMBINATION THERAPY FOR REDUCING SIDE EFFECTS USING CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-04-23 | — | — | US | disclosed |
| WO-2009052342-A1 | COMBINATION THERAPY FOR REDUCING SIDE EFFECTS USING CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-04-23 | — | — | WO | disclosed |
| US-20080242654-A1 | N-[(2Z)-3-butyl-4,5-dimethyl-1,3-thiazol-2(3H)-ylidene]-5-chloro-N',2-dimethoxybenzenecarboximidamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBOTT LABORATORIES (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080058335-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBVIE INC. | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312493-A1 | DEUTERATED AND TRITIATED N-(4,5-DIMETHYLTHIAZOLO-2(3H)-YLIDEN)-2,2,3,3-TETRAMETHYLCYCLOPROPANE-1-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF | CD22, CD2, CDY1; CDY1B | CNR2 514/4885CNR1 1015/4885PIM1 1849/4885 |
| US-20080242654-A1 | N-[(2Z)-3-butyl-4,5-dimethyl-1,3-thiazol-2(3H)-ylidene]-5-chloro-N',2-dimethoxybenzenecarboximidamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | CNR2, CNR1, TRPV1 | CNR2 1/4885CNR1 2/4885PIM1 4677/4885 |
| US-20100093814-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, OPRL1 | CNR2 2/4885CNR1 1/4885PIM1 3054/4885 |
| US-20090105304-A1 | COMBINATION THERAPY FOR REDUCING SIDE EFFECTS USING CANNABINOID RECEPTOR LIGANDS | CNR2, CNR1, GPR18 | CNR2 1/4885CNR1 2/4885PIM1 4789/4885 |
| US-20250027072-A1 | METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS | CNR1, CNR2, GPR3 | CNR2 2/4885CNR1 1/4885PIM1 2622/4885 |
| US-20080058335-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, OPRL1 | CNR2 2/4885CNR1 1/4885PIM1 3231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.