Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.59 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | CPA2 | P48052 | 1/20 | 0.53 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.53 |
| ▸ | FURIN | P09958 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450576 | 0.90 | GNPAT (0.47) | GNPATCPA1CPA2CPA4FURIN | |
| SCHEMBL3801766 | 0.86 | GNPAT (0.78) | GNPATCPA1CPA2CPA4FURIN | |
| SCHEMBL29550453 | 0.86 | GNPAT (0.78) | GNPATCPA1CPA2CPA4FURIN | |
| SCHEMBL3801759 | 0.86 | GNPAT (0.78) | GNPATCPA1CPA2CPA4FURIN | |
| SCHEMBL8933580 | 0.86 | GNPAT (0.78) | GNPATCPA1CPA2CPA4FURIN | |
| SCHEMBL29368954 | 0.86 | GNPAT (0.78) | GNPATCPA1CPA2CPA4FURIN | |
| SCHEMBL31181171 | 0.85 | GNPAT (0.69) | GNPATCPA1CPA2CPA4FURIN | |
| SCHEMBL9818098 | 0.85 | GNPAT (0.44) | GNPATCPA1CPA2CPA4FURIN | |
| SCHEMBL12285408 | 0.84 | CPA1 (0.59) | GNPATCPA1CPA2CPA4FURIN | |
| SCHEMBL15862955 | 0.83 | GNPAT (0.67) | GNPATCPA1CPA2CPA4FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564588-A4 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS | — | 1993-12-29 | — | — | EP | claimed |
| EP-0564588-A1 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS. | ABBOTT LAB (US) | 1993-10-13 | — | — | EP | claimed |