Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | FURIN | P09958 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | CPA2 | P48052 | 1/20 | 0.45 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450542 | 0.90 | GNPAT (0.59) | GNPATMMP2MMP1MMP3FURIN | |
| SCHEMBL9450587 | 0.89 | MMP1 (0.48) | GNPATMMP2MMP1MMP3SSTR3 | |
| SCHEMBL9450533 | 0.88 | MMP2 (0.50) | GNPATMMP2MMP1MMP3MMP9 | |
| SCHEMBL14821599 | 0.87 | MMP1 (0.57) | GNPATMMP2MMP1MMP3MMP9 | |
| SCHEMBL9450515 | 0.86 | MMP1 (0.50) | GNPATMMP2MMP1MMP3MMP9 | |
| SCHEMBL30917923 | 0.86 | GNPAT (0.61) | GNPATMMP2 | |
| SCHEMBL9818098 | 0.86 | GNPAT (0.44) | GNPATMMP2MMP1MMP3FURIN | |
| SCHEMBL9450513 | 0.85 | MMP2 (0.46) | GNPATMMP2MMP1MMP3ANPEP | |
| SCHEMBL23105976 | 0.85 | GNPAT (0.49) | GNPATMMP2MMP1MMP3OPRK1 | |
| SCHEMBL22845647 | 0.85 | GHSR (0.55) | GNPATFURINGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564588-A4 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS | — | 1993-12-29 | — | — | EP | claimed |
| EP-0564588-A1 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS. | ABBOTT LAB (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0456758-A1 | ANAPHYLATOXIN-RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1991-11-21 | — | — | EP | disclosed |