Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450599 | 0.76 | KDM4E (0.42) | BRD4ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL7712260 | 0.75 | POLB (0.59) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL9450622 | 0.72 | BRD4 (0.53) | BRD4CES1ALDH1A1KMT2AKDM4E | |
| SCHEMBL18485471 | 0.69 | KDM4E (0.53) | BRD4CES1ALDH1A1KMT2AKDM4E | |
| SCHEMBL22533232 | 0.69 | KMT2A (0.51) | BRD4ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL9348435 | 0.69 | ALDH1A1 (0.76) | CES1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL9450607 | 0.69 | ALDH1A1 (0.46) | BRD4ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL887161 | 0.66 | CES1 (0.62) | CES1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL22550209 | 0.65 | BRD4 (0.46) | BRD4ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL29774541 | 0.65 | BRD4 (0.46) | BRD4ALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229411-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | claimed |
| US-5229411-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | disclosed |