Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703132 | 0.79 | MAPT (0.61) | KDM4EKMT2AGAACASP1CASP7 | |
| SCHEMBL29180980 | 0.79 | CYP1B1 (0.52) | KDM4EKMT2AGAACASP1CASP7 | |
| SCHEMBL9450623 | 0.77 | PKM (0.51) | KDM4EKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9450604 | 0.76 | BRD4 (0.56) | KDM4EKMT2AGAACASP1HTT | |
| SCHEMBL30837374 | 0.76 | LMNA (0.40) | KDM4EKMT2AGAACASP1CASP7 | |
| SCHEMBL9450622 | 0.73 | BRD4 (0.53) | KDM4EKMT2AGAAHTTLMNA | |
| SCHEMBL7712260 | 0.73 | POLB (0.59) | KDM4EKMT2AHTTLMNAALDH1A1 | |
| SCHEMBL9450607 | 0.72 | ALDH1A1 (0.46) | KDM4EKMT2AGAAHTTLMNA | |
| SCHEMBL29180967 | 0.71 | KMT2A (0.37) | KDM4EKMT2AGAACASP1CASP7 | |
| SCHEMBL30837377 | 0.71 | KMT2A (0.37) | KDM4EKMT2AGAACASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229411-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | claimed |
| US-5229411-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | disclosed |