Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.44 |
| ▸ | CASP7 | P55210 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TYMS | P04818 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450598 | 0.80 | KDM4E (0.53) | POLBALPLKDM4EALDH1A1HPGD | |
| SCHEMBL9450628 | 0.78 | KDM4E (0.52) | POLBALPLKDM4EALDH1A1HPGD | |
| SCHEMBL9450619 | 0.76 | KDM4E (0.50) | POLBALPLKDM4EALDH1A1HPGD | |
| SCHEMBL7307793 | 0.76 | CDK5 (0.54) | POLBALPLKDM4EALDH1A1HPGD | |
| SCHEMBL9450641 | 0.72 | CDK5 (0.50) | POLBALPLKDM4EALDH1A1HPGD | |
| SCHEMBL11322480 | 0.71 | KDM4E (0.53) | POLBALPLKDM4EALDH1A1HPGD | |
| SCHEMBL10952664 | 0.70 | KDR (0.48) | POLBALPLKDM4EALDH1A1HPGD | |
| SCHEMBL11809624 | 0.70 | BCL2 (0.50) | POLBALPLKDM4EALDH1A1HPGD | |
| SCHEMBL11316606 | 0.69 | KDM4E (0.63) | POLBALPLKDM4EALDH1A1HPGD | |
| SCHEMBL14712322 | 0.68 | KDM4E (0.58) | POLBALPLKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229411-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | claimed |
| US-5229411-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | disclosed |