SCHEMBL9450826

SCHEMBL9450826

CC(Nc1ccccc1)NS(C)(=O)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.52
TDP1 Q9NUW8 2/20 0.50
CYP3A4 P08684 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALDH1A1 P00352 2/20 0.44
ALOX15 P16050 2/20 0.44
TSHR P16473 2/20 0.44
ALOX12 P18054 2/20 0.44
HSD17B10 Q99714 2/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
ATM Q13315 1/20 0.44
GAA P10253 1/20 0.39
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
PGR P06401 1/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL8070180 0.94 KEAP1 (0.47) KEAP1TDP1CYP3A4L3MBTL1ALDH1A1
Sulfuric Acid SCHEMBL8645603 0.93 KEAP1 (0.46) KEAP1TDP1CYP3A4L3MBTL1ALDH1A1
SCHEMBL9289658 0.81 ALDH1A1 (0.38) KEAP1CYP3A4L3MBTL1ALDH1A1TSHR
SCHEMBL990038 0.78 TDP1 (0.70) TDP1CYP3A4L3MBTL1ALDH1A1ALOX15
Sulfuric Acid SCHEMBL11087468 0.77 ALDH1A1 (0.38) KEAP1TDP1CYP3A4L3MBTL1ALDH1A1
Hydrochloric Acid SCHEMBL11372580 0.75 TDP1 (0.67) TDP1CYP3A4L3MBTL1ALDH1A1ALOX15
SCHEMBL30833748 0.75 TDP1 (0.54) KEAP1TDP1CYP3A4L3MBTL1ALDH1A1
SCHEMBL11308263 0.72 TDP1 (0.61) TDP1CYP3A4L3MBTL1ALDH1A1ALOX15
SCHEMBL14535198 0.72 TDP1 (0.61) KEAP1TDP1CYP3A4L3MBTL1ALDH1A1
SCHEMBL3885828 0.71 CNR2 (0.57) CYP3A4ALDH1A1HSD17B10CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0167173-B2 Color photographic materials FUJI PHOTO FILM CO LTD (JP) 1993-11-10 EP disclosed
US-5187057-A Silver halide emulsion layer containing novel coupler on a substrate images are heat, moisture and light fast KONICA CORPORATION (JP) 1993-02-16 US disclosed
US-5071737-A Durability against heat, humidity and light KONICA CORPORATION (JP) 1991-12-10 US disclosed
US-5015560-A Purification of photographic solutions bu absorption on a resin KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1991-05-14 US disclosed
US-4985118-A Method for treating photographic process waste liquor through concentration by evaporation KONICA CORPORATION (JP) 1991-01-15 US disclosed
US-4977073-A Color reprocibility KONICA CORPORATION (JP) 1990-12-11 US disclosed
EP-0161626-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1990-12-05 EP disclosed
US-4959122-A EVAPORATION, PRECIPITATION, THERMAL DECOMPOSITION KONICA CORPORATION (JP) 1990-09-25 US disclosed
EP-0136142-B1 THERMALLY DEVELOPABLE, LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-11 EP disclosed
EP-0114674-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-04-12 EP disclosed
EP-0309957-A1 Stabilizers for colour-photographic recording materials CIBA-GEIGY AG (CH) 1989-04-05 EP disclosed
US-4753868-A SENSITIZER DYES FUJI PHOTO FILM CO., LTD. (JP) 1988-06-28 US disclosed
US-4546068-A AROMATIC AMINE DEVELOPER, MANANESE AND OR CERIUM SALT, DIPHOSPHONIC ACID SEQUESTERING AGENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-10-08 US disclosed
US-4537856-A WATER SOLUBLE CHELATE COMPOUND AS STABILIZER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-08-27 US disclosed
US-4473374-A Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1984-09-25 US disclosed
US-4330291-A Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1982-05-18 US disclosed
US-4301223-A ADDITION OF A METAL COMPLEX FUJI PHOTO FILM CO., LTD. (JP) 1981-11-17 US disclosed
US-4279990-A SILANOL AND SILANEDIOL COMPOUNDS TO PREVENT DISCOLORATION FUJI PHOTO FILM CO., LTD. (JP) 1981-07-21 US disclosed