Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963141 | 0.88 | RAB9A (0.41) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL8963136 | 0.88 | RAB9A (0.41) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL8963100 | 0.87 | RAB9A (0.41) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL8963105 | 0.87 | RAB9A (0.41) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL8962748 | 0.85 | SMN1; SMN2 (0.35) | RAB9AMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL8962756 | 0.85 | SMN1; SMN2 (0.35) | RAB9AMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL9299861 | 0.82 | DRD2 (0.39) | DRD2DRD4DRD3NPBWR1 | |
| SCHEMBL9299863 | 0.82 | DRD2 (0.39) | DRD2DRD4DRD3NPBWR1 | |
| SCHEMBL9450903 | 0.79 | SPHK1 (0.52) | CASP3SENP8SENP7SENP6DRD2 | |
| SCHEMBL11502287 | 0.76 | RAB9A (0.50) | CASP3SENP8SENP7SENP6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-A1 | HALOVINYL-DERIVATIVES. | HOFFMANN LA ROCHE (CH) | 1993-09-15 | — | — | EP | disclosed |
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |